Is this a repost? I’ve seen this exact same post somewhere.

Anyway, SimpleX may not be decentralized OOTB, but can be made to be since their relays are self-hostable. It should be as simple as spinning up an instance and changing the url in app.

IMO the title is incorrect because the common interpretation of getting “burned out” is that of the same individuals of a population losing effectiveness after working hard. The article even likens the term “exhausted” the same interpretation of the phrase:

Altogether, our research suggests that T cells in tumors are not necessarily working hard and getting exhausted. Rather, they are blocked right from the start.

This same quote describes the truth of the phenomenon where it’s not individuals getting “exhausted”, but cellular signalling permanently altering the expression of T cells to make them less and less effective.

A more correct title would be something like:

Cancer makes every generation of T cells worse than the last

Isn’t this a strange article title? The whole point of it is to show T cells don’t actually get “burned out” at all. And imo it’s not like the real reason is uninteresting.

Why dress the article in the exact thing it’s refuting?

Are you still using it? I went through many deployments before I finally thought I had it settled.

At the beginning of the pandemic I looked into ways to de-Google and found Nextcloud. It wasn’t the easiest thing to start with, especially for a novice, but I had the time and the hardware, and I’m the type to not mind jumping into something difficult if it means solving a specific problem. I then found out about Bitwarden and had a great experience setting that up. After that I was confident enough to try hosting anything I could find. It’s been good times ever since 😀

This is extremely valuable, thanks for this!

As a general question, why did you decide to use a single postgres container for multiple services instead of multiple, stack specific containers? When I first started working with containers I considered your scheme for the sake of minimalism, but didn’t want a single container to bring down multiple unrelated services. I also had the resources to accomodate the redundancy.